PROGRAM
Toward Elimination of Viral Hepatitis:
Achievements, Challenges, and Prospects
September 21-23, 2023 ㅣ BEXCO, Busan, Korea
08:30-09:30
Symposium 2-1. Circulating HBV Markers: What Are Their Roles?
Tarik Asselah (Hepatology at Hôpital Beaujon, France), Jung-Hwan Yoon (Seoul National Univ., Korea)
Ultra-High Sensitivity HBsAg and Anti-HBc in Managing Chronic Hepatitis B
Jihyun An (Hanyang Univ., Korea)
HBcrAg and HBV RNA in Managing Chronic Hepatitis B
Lung-Yi Mak (The Univ. of Hong Kong, Hong Kong)
Circulating Virus-Host Chimera DNA for Monitoring Virus-Related HCC
Shiou-Hwei Yeh (National Taiwan Univ., Taiwan)
Plenary Session
Coffee Break
10:50-11:50
Symposium 2-4. Direction to Pursue in Hepatitis C Treatment
Chun-Jen Liu (National Taiwan Univ., Taiwan), Seung Woon Paik (Sungkyunkwan Univ., Korea)
How to Manage Patients with DAA Treatment Failure
Young-Joo Jin (Inha Univ., Korea)
How to Manage Difficult-to-Cure Patients: Decompensated Disease and Transplantation
In Hee Kim (Jeonbuk National Univ., Korea)
Managing Drug-Drug Interaction, Adherence, and Adverse Events in the Era of Pangenotypic DAA
Woo Jin Chung (Keimyung Univ., Korea)
Multidisciplinary Approach to Predict Fibrosis Progression and HCC after DAA Therapy
Tawesak Tanwandee (Mahidol Univ., Thailand)
Luncheon Symposium [Gilead] AGENDA
12:50-13:20
State-of-the-Art Lecture 2
Jin Mo Yang (The Catholic Univ. of Korea, Korea)
The Road to Curing Hepatitis B Virus Infection: Past, Present, and Future
George Lau (Humanity and Health Medical Group, Hong Kong)
13:20-14:20
Keynote Lecture 2. Cure of Viral Hepatitis. Is this Safe against the Development of HCC?
Jia-Horng Kao (National Taiwan Univ., Taiwan), Kyung-Suk Suh (Seoul National Univ., Korea)
Genetic Polymorphism & Family History as a Non-Modifiable Risk Factor for HCC after HBV Cure
Yoon Jun Kim (Seoul National Univ., Korea)
Viral Persistence after a Functional Cure and HCC Risk
Jia-Horng Kao (National Taiwan Univ., Taiwan)
Mechanisms of Hepatocarcinogenesis after HCV Eradication
Raymond T. Chung (Harvard Univ., USA)
Coffee Break
14:40-16:00
APASL-AASLD Joint Session. A New Area of Interest in Chronic Hepatitis B: To Treat or Not to Treat
Norah Terrault (Univ. of Southern California, USA), Si Hyun Bae (The Catholic Univ. of Korea, Korea)
Classification and Clinical Characteristics of Gray-Zone in Chronic Hepatitis B
Marc G. Ghany (NIH, USA)
HBeAg-Positive "Gray-Zone": Should We Treat and Why?
Tai-Chung Tseng (National Taiwan Univ., Taiwan)
HBeAg-Negative "Gray-Zone": Should We Treat and Why?
Jordan Feld (Univ. of Toronto, Canada)
Optimizing Non-Invasive Methods to Identify Gray-Zone Patients with Liver Fibrosis
Seung Up Kim (Yonsei Univ., Korea)
Coffee Break
16:20-17:40
Symposium 2-7. Debate Session. Strategies to Achieve HBsAg Seroclearance
W. Ray Kim (Stanford Univ., USA), Maria Buti Ferret (Hospital Universitario Valle Hebron, Spain)
Stopping Antivirals
Wen-Juei Jeng (Chang Gung Univ., Taiwan)
Continuing Antivirals
Jonggi Choi (Ulsan Univ., Korea)
Interferon or Interferon-Based Therapy
Tarik Asselah (Hepatology at Hôpital Beaujon, France)
Newer Antiviral Agents: Next Steps to Combination Therapy
Robert G. Gish (Hepatitis B Foundation, USA)
Panel Discussion
08:30-09:30
Symposium 2-2. Update of Cirrhosis and Portal Hypertension
Shiv Kumar Sarin (Institute of Liver & Biliary Sciences, India), Dong Joon Kim (Hallym Univ., Korea)
Liver and Spleen Stiffness for the Estimation of Portal Hypertension and Cirrhotic Complications
Moonyoung Kim (Yonsei Univ. Wonju, Korea)
Antiviral Therapy and the Outcome of Patients with Decompensated Cirrhosis
Sung Eun Kim (Hallym Univ., Korea)
Optimal Assessment and Improving Survival in Acute Variceal Bleeding
Shiv Kumar Sarin (Institute of Liver & Biliary Sciences, India)
The Role of Antibiotic Therapy in Acute Decompensation
Jung Gil Park (Yeungnam Univ., Korea)
09:30-10:30
Symposium 2-3. Non-B Non-C Viral Hepatitis: Pathogenesis and Treatment
Jaeseok Hwang (Keimyung Univ., Korea), Hee Bok Chae (Chungbuk National Univ., Korea)
Immunopathogenesis of Acute Hepatitis A
Eui-Cheol Shin (KAIST, Korea)
Novel Therapies for Hepatitis D virus
Young Eun Chon (CHA Univ., Korea)
Disease Burden and Potential Therapeutic Approach to HEV Infection
Lubna Kamani (Liaquat National Hospital, Pakistan)
Pathogenesis and Management of Non-Hepatotropic Viruses
Ju-Yeon Cho (Chosun Univ., Korea)
Coffee Break
10:50-11:50
Symposium 2-5. Metabolic Disease and Viral Hepatitis
Jose D. Sollano (The Univ. of Santo Tomas, Philippines), Sang Hoon Park (Hallym Univ., Korea), Oh Sang Kwon (Gachon Univ., Korea)
Role of Metabolic Risk Factors in the Outcome of Viral Hepatitis
Lai Wei (Tsinghua Univ., China)
Effects of Alcohol Drinking on the Prognosis of Patients with Viral Hepatitis
Won Kim (Seoul National Univ., Korea)
MAFLD in Chronic Hepatitis B: Friend or Foe?
Lung-Yi Mak (The Univ. of Hong Kong, Hong Kong)
Management Strategies for Viral Hepatitis with Concurrent MAFLD
Hye Won Lee (Yonsei Univ., Korea)
Luncheon Symposium [Yuhan] AGENDA
Coffee Break
14:40-16:00
Symposium 2-6. Prevention and Surveillance of Viral Hepatitis-Associated HCC
Shuichiro Shiina (Juntendo Univ., Japan), Joong-Won Park (National Cancer Center, Korea), Jong Young Choi (The Catholic Univ. of Korea, Korea)
Anti-HBV Therapy to Prevent HBV-Associated HCC
Tetsuya Hosaka (Toranomon Hospital, Japan)
Anti-HCV Therapy to Prevent HCV-Associated HCC
Do Young Kim (Yonsei Univ., Korea)
Non-Viral Managements to Prevent HCC
Dong Hyun Sinn (Sungkyunkwan Univ., Korea)
Risk-Stratified Surveillance for Hepatitis Virus-Associated HCC
Shuichiro Shiina (Juntendo Univ., Japan)
Coffee Break
16:20-17:40
Symposium 2-8. AI & Machine Learning for Liver Disease Management
Moon Seok Choi (Sungkyunkwan Univ., Korea), Il Han Song (Dankook Univ., Korea)
Developing AI Model for Predicting HCC
Hwi Young Kim (Ewha Womans Univ., Korea)
Radiomics and Deep Learning for Chronic Liver Disease
Roongruedee Chaiteerakij (Chulalongkorn Univ., Thailand)
Harnessing Knowledge and Experimental Data Using AI Drug Discovery Technology
Han Jo Kim (Standigm, Korea)
Deep Learning-Based Prediction of Biomarkers Using Liver Cancer Histopathological Images
Sung Hak Lee (The Catholic Univ. of Korea, Korea)
07:30-08:20
Early Morning Workshop 1. Emerging Risk Factors of HCC in Chronic Hepatitis B
Diana A. Payawal (Fatima Medical Univ., Philippines)
Impact of Metabolic Factors on the Risk of HBV-Related HCC
Yun Bin Lee (Seoul National Univ., Korea)
Have Risk Factors for HCC Changed over the Decades?
Roongruedee Chaiteerakij (Chulalongkorn Univ., Thailand)
Discussion
Discussants: Yun Bin Lee (Seoul National Univ., Korea), Roongruedee Chaiteerakij (Chulalongkorn Univ., Thailand), Kang Mo Kim (Univ. of Ulsan, Korea), Tai-Chung Tseng (National Taiwan Univ., Taiwan)
09:30-10:30
SIG 2. cccDNA and HBV Integration: Stumbling Blocks for HBV Cure
Byung-Cheol Song (Jeju Univ., Korea), Kyun-Hwan Kim (Sungkyunkwan Univ., Korea)
HBV cccDNA: Mechanism of Its Formation and Therapeutic Targets
Kyun-Hwan Kim (Sungkyunkwan Univ., Korea)
HBV Integration and Liver Cancer
Thomas Tu (Westmead Institute for Medical Research, Australia)
Genome Editing for cccDNA and Integrated HBV
Jae Young Lee (ToolGen, Korea)
10:50-11:50
SIG 3. Immunopathogenesis of Viral Hepatitis
Jeong Heo (Pusan National Univ., Korea), Eui-Cheol Shin (KAIST, Korea)
Type I and Type III Interferon Responses in Hepatitis Virus Infection
Pil Soo Sung (The Catholic Univ. of Korea, Korea)
T-Cell Responses and Immunopathogenesis of Chronic Hepatitis B
Yuri Cho (National Cancer Center, Korea)
Characteristics of B-Cells in HBV-Associated Chronic Liver Disease
Ji Eun Oh (KAIST, Korea)
Chronic Hepatitis and Liver Fibrosis in Humans
Hideki Ueno (Kyoto Univ., Japan)
Luncheon Symposium [Daewoong] AGENDA
13:20-14:20
Hepatology Associates - Education Forum 1. Approach to Various Chronic Liver Disease (*K)
Tae Hun Kim (Ewha Womans Univ., Korea), Jung Woo Shin (Univ. of Ulsan, Korea)
Treatment of Chronic Hepatitis B: When and Whom?
Jae Yoon Jeong (National Medical Center, Korea)
Diagnosis and Management of Hepatitis C Virus Infection
Woo Sun Rou (Chungnam National Univ.)
Diagnosis and Management of Autoimmune Hepatitis
Young Chang (Soonchunhyang Univ., Korea)
Surveillance and Diagnosis of HCC
Han Ah Lee (Ewha Womans Univ., Korea)
Coffee Break
14:40-16:00
Hepatology Associates - Education Forum 2. Metabolism, Alcohol and Toxicity (*K)
Byung Seok Lee (Chungnam National Univ., Korea), Gab Jin Cheon (Univ. of Ulsan, Korea)
Epidemiology, Natural History and Risk Stratification of NAFLD
Yang-Hyun Baek (Dong-A Univ., Korea)
Lifestyle Intervention and Available Medications in NAFLD Treatment
Se Young Jang (Kyungpook National Univ., Korea)
Management of Severe Alcoholic Hepatitis
Tae Suk Kim (Kangwon National Univ., Korea)
Updated Guideline on Drug-Induced Liver Injury
Nae-Yun Heo (Inje Univ., Korea)
Coffee Break
16:20-17:20
Hepatology Associates - Education Forum 3. Cirrhosis and Complications, Case-Based Learning (*K)
Chang Hyeong Lee (Daegu Catholic Univ., Korea), Young Seok Kim(Soonchunhyang Univ., Korea)
Diagnosis and Management of Ascites and Related Complications
Chang Hun Lee (Jeonbuk National Univ., Korea)
Diagnosis and Management of Acute Variceal Bleeding
Seong Hee Kang (Korea Univ., Korea)
When Is the Appropriate Time for Liver Transplantation?
Kwang Il Seo (Kosin Univ., Korea)
Treatment Strategy Based on HCC Stage
Jung Hwan Yu (Inha Univ., Korea)
07:30-08:20
Early Morning Workshop 2. Real-Life Experiences in HCV Management
Ming-Lung Yu (National Sun Yat-sen Univ., Taiwan)
Are Metabolic Derangements Corrected after Cure of HCV?
Eun Ju Cho (Seoul National Univ., Korea)
Effects of DAA Treatment on Extrahepatic Manifestations in HCV Infection
Hyun Phil Shin (Kyung Hee Univ., Korea)
Discussion
Discussants: Eun Ju Cho (Seoul National Univ., Korea), Hyun Phil Shin (Kyung Hee Univ., Korea), Tetsuya Hosaka (Toranomon Hospital, Japan), Geum-Youn Gwak (Sungkyunkwan Univ., Korea)